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Cholic acid, sodium salt hydrate
Cat. No.:
OB0626WX-123
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Cholic acid is a primary bile acid biosynthesized from cholesterol through a multi-step enzymatic cascade orchestrated by cytochrome P450 isoforms CYP7A1, CYP8B1, and CYP27A1, which then undergo hepatic conjugation to glycine or taurine via bile acid-CoA:amino acid N-acyltransferase (BAAT) to yield glycocholic acid and taurocholic acid, respectively, before being biotransformed into the secondary bile acid deoxycholic acid by commensal gut microbiota.
Synonyms:
(5β)-3α,7,12α-trihydroxy-cholan-24-oic acid, sodium salt hydrate; CA; Cholalic Acid; Cholalin; Sodium cholate hydrate; Cholalic acid sodium salt xhydrate; sodium;(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;hydrate; 206986-87-0
CAS No.:
206986-87-0
Compound CID:
23679061
Formula:
C24H39O5 • Na [XH2O]
Formula Weight:
488.6
Specification
Solubility in DMSO:
≥10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
Cholic acid, sodium salt hydrate serves as a bile acid-derived surfactant reference compound for investigating micelle formation, membrane interactions, and lipid solubilization properties. It supports membrane biochemistry studies, protein reconstitution workflows, and characterization of bile acid-associated structures.