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C2 Adamantanyl Gb3 (d18:1/2:0)
Cat. No.:
OB0626WX-126
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by TLC.
Size:
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Product Overview
Description:
C2 Adamantanyl Gb3 (d18:1/2:0) is a highly bioactive, water-soluble structural analog of globotriaosylceramide incorporating a rigid adamantanyl cage group in place of the native fatty acyl chain structure. This engineered sphingolipid functions as an effective competitive inhibitor that blocks Vero toxin binding to endogenous globotriaosylceramide receptors.
Synonyms:
N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-tricyclo[3.3.1.13,7]decane-1-acetamide; AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0); C2 Adamantanyl Globotriaosylceramide (d18:1/2:0); 261155-87-7; 2-(1-adamantyl)-N-[(E,2S,3R)-1-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]acetamide
CAS No.:
261155-87-7
Compound CID:
101011089
Formula:
C48H83NO18
Formula Weight:
962.2
Specification
Solubility in DMF:
Soluble
Solubility in Other Solvents:
Soluble in chloroform and methanol.
Storage:
Storage at -20°C.
Applications:
C2 Adamantanyl Gb3 (d18:1/2:0) serves as a modified glycolipid analogue for investigating glycosphingolipid organization, membrane microdomain properties, and carbohydrate-mediated molecular interactions. It supports model membrane studies, glycolipid characterization, and analysis of structural effects on lipid organization.