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BW 755C
Cat. No.:
OB0225WX-1853
Appearance:
Solid
Purity:
≥96%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
BW 755C is a dual-pathway chemical inhibitor that simultaneously targets the cyclooxygenase (COX) and 5-lipoxygenase (5-LO) enzymatic systems.
Synonym:
66000-40-6; BW-755C; BW755C; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 1-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-pyrazol-3-amine; 2-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazol-5-amine; 3-Amino-1-(3-(trifluoromethyl)phenyl)-2-pyrazoline; 1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)-; 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine; 1-(3-(trifluoromethyl)phenyl)-4,5-dihydro-1H-pyrazol-3-amine; 1-(3-trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-(3-trifluoromethylphenyl)-2-pyrazoline; 1-[3-(trifluoromethyl)phenyl]-3-amino-2-pyrazoline; 3-amino-1-(m-(trifluoromethyl)phenyl)-2-pyrazoline; 1-(3-trifluoromethylphenyl)-4,5-dihydro-1H-3-pyrazolamine; 3-amino-1-(alpha,alpha,alpha-trifluoro-m-tolyl)-2-pyrazoline; 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine (BW-755C); 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine(BW 755 C); 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine(BW 755C)
CAS No.:
66000-40-6
Compound CID:
47795
Formula:
C10H10F3N3
Formula Weight:
229.2
Specification
Targets&IC50:
COX-2: 1.2 μg/mL; 5-LOX: 0.75 μM; COX-1: 0.65 μg/mL
Relative Density:
1.40 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
BW 755C is utilized in biochemical studies as a dual inhibitor of cyclooxygenase and lipoxygenase to investigate the simultaneous blockage of prostaglandin and leukotriene formation.
Library Information
Target:
Lipoxygenase
Receptor:
5-LOX
Pathways:
Metabolism
Plate Number:
AOCL-24
Plate Location:
g4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
25 mg/mL; 109.03 mM
Ethanol Max Solubility:
20 mg/mL; 87.22 mM





