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AMG-076 free base
Cat. No.:
OB0425LY-009
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
AMG-076 free base is an orally bioavailable and selective MCHR1 antagonis that associated with weight management.
Synonyms:
Cyclohexanecarboxylic acid, 1-(2-((4aR,11R,11aS)-1,3,4,4a,5,6,11,11a-Octahydro-11-methyl-9-(trifluoromethyl)-2H-pyrido(4,3-b)carbazol-2-yl)ethyl)-; 1-(2-((4aR,11R,11aS)-11-Methyl-9-(trifluoromethyl)-3,4,4a,5,11,11a-hexahydro-1H-pyrido[4,3-b]carbazol-2(6H)-yl)ethyl)cyclohexanecarboxylic acid; 1-[2-[(4aR,11R,11aS)-11-Methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid
CAS No.:
693823-79-9
Compound CID:
10004545
Formula:
C26H33F3N2O2
Formula Weight:
462.55
Specification
Target:
MCHR1 (GPR24)
Pathway:
GPCR/G protein; Neuronal signaling
Storage:
Storage at -20°C.
Applications:
AMG-076 free base can be used for weight management in high-fat diet-fed non-obese mice and high-fat diet-induced obese (DIO) mice.
