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8-iso PGF2α-d4
Cat. No.:
OB0626WX-3164
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1–d4)
Identity:
Confirmed by TLC and HPLC.
Size:
Add to basket
Product Overview
Description:
8-iso PGF2α-d4 is a stable isotope internal standard featuring four deuterium atoms designed for highly accurate mass spectrometric calibration. The native analyte is a prominent isoprostane generated via the non-enzymatic peroxidation of membrane phospholipids, circulating across systemic compartments as both a free acid and a phospholipid-bound ester, where it functions as an attenuated thromboxane receptor agonist in vascular walls while concurrently modulating specific ligand-induced platelet aggregation cascades.
Labeling:
Stable isotope-labeled
Synonyms:
9α,11α,15S-trihydroxy-(8β)-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid; iPF2α-III-d4; 8-Isoprostane-d4; 15-F2t-Isoprostane-d4; 8-epi PGF2α-d4; 8-iso Prostaglandin F2alpha-d4; 211105-40-7; 8-Iso-PGF2a-d4; (Z)-3,3,4,4-Tetradeuterio-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid; 8-isoPGF2alpha-d4; 8-Isoprostaglandin F2alpha-d4; 9S,11R,15S-trihydroxy-5Z,8-iso Prostaglandin F2alpha-d4; 13E-prostadienoic acid-cyclo[8S,12R]-d4
CAS No.:
211105-40-7
Compound CID:
90471027
Formula:
C20H30D4O5
Formula Weight:
358.5
Specification
Solubility in DMSO:
>100 mg/mL
Solubility in Ethanol:
>100 mg/mL
Solubility in DMF:
>100 mg/mL
Solubility in Other Solvents:
Na2CO3: >6.5 mg/mL; PBS: >10 mg/mL
Storage:
Storage at -20°C.
Applications:
8-iso PGF2α-d4 provides an isotope-labeled analytical standard for quantitative detection of isoprostane lipid oxidation products. It supports isotope dilution LC-MS/MS analysis, calibration, and accurate characterization of oxidative lipid metabolites.