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7α-hydroxy Cholesterol-d7
Cat. No.:
OB0626WX-1816
Appearance:
Solid
Purity:
≥99% (deuterated forms, d1-d7)
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
7α-hydroxy Cholesterol-d7 is a stable isotope-labeled internal standard engineered for the precise mass spectrometric quantification of 7α-hydroxy cholesterol. The native oxysterol analyte serves as the initial, rate-limiting precursor in the hepatic conversion of cholesterol into classic bile acids and acts as an endothelial signaling mediator that upregulates vascular cell adhesion molecules and chemokine secretion networks.
Labeling:
Stable isotope-labeled
Synonyms:
Cholest-5-ene-25,26,26,26,27,27,27-d7-3β,7α-diol; 7α-hydroxycholesterol-d7; 7alpha-hydroxycholesterol-d7; 7|A-Hydroxycholesterol-d7; Cholesterol Impurity 37; 7alpha-hydroxy-cholesterol(d7); cholest-5-en-3beta,7alpha-diol(d7); Cholest-5-ene-25,26,26,26,27,27,27-d7-3,7-diol, (3ss,7a)-; 7a-Hydroxycholesterol-25,26,26,26,27,27,27-D7; 7a-Hydroxycholesterol-d7; 349553-94-2
CAS No.:
349553-94-2
Compound CID:
3247055
Formula:
C27H39D7O2
Formula Weight:
409.7
Specification
Solubility in DMSO:
0.1 mg/mL
Solubility in Ethanol:
20 mg/mL
Solubility in DMF:
2 mg/mL
Storage:
Storage at -20°C.
Applications:
7α-hydroxy Cholesterol-d7 operates as a stable isotope-labeled oxysterol internal standard designed for quantitative lipidomics, providing a distinct mass shift that secures precision in isotope dilution mass spectrometry workflows and balances extraction variations during bile acid pathway investigations.