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5α,6α-epoxy Cholestanol
Cat. No.:
OB0626WX-1735
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
5α,6α-epoxy Cholestanol is an oxidized oxysterol metabolite generated through the systemic peroxidation of native cholesterol. This signaling molecule accumulates dynamically within breast adenocarcinoma frameworks under reactive oxygen species-driven conditions following specific pharmacological challenges, where it induces neutral triacylglycerol biosynthesis via direct interaction with liver X receptor beta, while its fluctuating anatomical tissue levels serve as an indicator of lipid dysregulation in vascular pathologies and post-mortem neurodegenerative models.
Synonyms:
(3β,5α,6α)-5,6-epoxy-cholestan-3-ol; Cholesterol 5α,6α-epoxide; 5α,6α-Epoxycholesterol; Cholesterol alpha-oxide; 5,6-epoxycholesta-3-ol; Cholestan-5 alpha,6 alpha-epoxy-3 beta-ol; Cholesterol alpha-epoxide; Cholesterol-5 alpha,6 alpha-epoxide; Cholesterol-5 alpha,6 alpha-oxide; cholesterol 5,6-epoxide; 1250-95-9
CAS No.:
1250-95-9
Compound CID:
227037
Formula:
C27H46O2
Formula Weight:
402.7
Specification
Solubility in DMSO:
0.1 mg/mL
Solubility in Ethanol:
20 mg/mL
Solubility in DMF:
2 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.3 mg/mL
Storage:
Storage at -20°C.
Applications:
5α,6α-epoxy Cholestanol acts as an oxysterol pathway derivative standard to map downstream cellular sterol degradation cascades, calibrate high-resolution quantitative separation protocols, and analyze how steroid ring epoxidation modifies the lateral cohesive packing metrics of model lipid monolayers.