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SRT2104 (GSK2245840)
Cat. No.:
OB0225WX-2707
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
SRT2104 (GSK2245840) is a selective molecular activator of SIRT1 that plays a key role in the biochemical regulation of energy homeostasis.
Synonym:
1093403-33-8; SRT2104; SRT 2104; SRT-2104; 4-Methyl-n-(2-(3-(morpholinomethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-(pyridin-3-yl)thiazole-5-carboxamide; 5-Thiazolecarboxamide, 4-methyl-N-[2-[3-(4-morpholinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(3-pyridinyl)-; 4-Methyl-N-(2-{3-[(morpholin-4-yl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide; 4-Methyl-N-[2-[3-(morpholin-4-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-pyridin-3-yl-1,3-thiazole-5-carboxamide; 4-Methyl-N-[2-[3-(morpholinomethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(pyridin-3-yl)thiazole-5-carboxamide
CAS No.:
1093403-33-8
Compound CID:
25108829
Formula:
C26H24N6O2S2
Formula Weight:
516.64
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SRT2104 (GSK2245840) is employed in metabolic and aging research as a selective SIRT1 activator to investigate the enhancement of mitochondrial function and the regulation of metabolic homeostasis.
Library Information
Target:
Sirtuin
Receptor:
SIRT1
Pathways:
DNA damage/DNA repair
Plate Number:
L6700-09
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
2mM DMSO
DMSO Max Solubility:
4 mg/mL; 7.74 mM
ALogP:
2.813
HBA_Count:
5
HBD_Count:
1
Rotatable Bond:
6





