Elimusertib

Cat. No.: OB0225WX-2338

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

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Product Overview

Description: Elimusertib is a highly selective and orally bioavailable ATR inhibitor with a nanomolar IC50 of 7 nM.

Synonym: BAY-1895344; 1876467-74-1; BAY 1895344; BAY1895344; (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridin-2-yl)morpholine; BAY-1895344 HCl; (3R)-3-methyl-4-[4-(2-methylpyrazol-3-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine; (3R)-3-methyl-4-(4-(2-methylpyrazol-3-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine; (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine; 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine; BAY-1895344; 2-[(3R)-3-methylmorpholin-4-yl]-4-(2-methylpyrazol-3-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine

CAS No.: 1876467-74-1

Compound CID: 118869362

Formula: C₂₀H₂₁N₇

Formula Weight: 375.43

Specification

Targets&IC50: ATR: 7 nM (IC50)

Relative Density: 1.43 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Elimusertib is utilized in advanced oncology research as a potent and selective ATR inhibitor to investigate the disruption of replication stress responses and the enhancement of DNA-damaging therapies.