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BMS-687453
Cat. No.:
0225LY-0919
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
BMS-687453 is a selective and potent PPAR alpha agonist with an EC50 of 10 nM for the human receptor, demonstrating approximately 410-fold selectivity compared to human PPAR gamma.
Synonym:
1000998-59-3; Glycine, N-[[3-[[2-(4-chlorophenyl)-5-methyl-4-oxazolyl]methoxy]phenyl]methyl]-N-(methoxycarbonyl)-; BMS 687453; N-(3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine; 2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}phenyl)methyl](methoxycarbonyl)amino}acetic acid; Glycine, N-((3-((2-(4-chlorophenyl)-5-methyl-4-oxazolyl)methoxy)phenyl)methyl)-N-(methoxycarbonyl)-; N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine
CAS No.:
1000998-59-3
Compound CID:
16725047
Formula:
C22H21ClN2O6
Formula Weight:
444.86
Specification
Targets&IC50:
PPARα (human): 260 nM
Relative Density:
1.342 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
BMS-687453 can be used in pharmacological studies to explore its potency as a selective agonist for the PPAR-alpha receptor.
Library Information
Target:
PPAR
Receptor:
PPARα
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
g10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
31 mg/mL; 69.68 mM
