AZD0156

Cat. No.: OB0225WX-2342

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: AZD0156 is a specific and effective small molecule inhibitor of ATM kinase that possesses intrinsic chemosensitizing and radiosensitizing molecular properties.

Synonym: 1821428-35-6; AZD-0156; 2H-Imidazo[4,5-c]quinolin-2-one, 8-[6-[3-(dimethylamino)propoxy]-3-pyridinyl]-1,3-dihydro-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-; Azd 0156; AZD 0156 [WHO-DD]; 8-[6-[3-(dimethylamino)propoxy]pyridin-3-yl]-3-methyl-1-(oxan-4-yl)imidazo[4,5-c]quinolin-2-one; 8-(6-(3-(dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one; 8-(6-(3-(dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(oxan-4-yl)imidazo(4,5-c)quinolin-2-one; 8-{6-[3-(dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(oxan-4-yl)imidazo[4,5-c]quinolin-2-one; MFCD30470661; 8-(6-(3-(Dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo(4,5-c)quinolin-2-one; 8-(6-(3-(Dimethylamino)propoxy)pyridin-3-yl)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one; 8-[6-(3-Dimethylaminopropoxy)pyridin-3-yl]-3-methyl-1-(oxan-4-yl)imidazo[5,4-c]quinolin-2-one

CAS No.: 1821428-35-6

Compound CID: 118502708

Formula: C₂₆H₃₁N₅O₃

Formula Weight: 461.56

Specification

Targets&IC50: ATM: 0.58 nM

Relative Density: 1.242 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: AZD0156 is utilized in oncological studies as a highly potent ATM inhibitor to study the potentiation of PARP inhibitors and the induction of synthetic lethality in DNA-repair-deficient tumors.