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T0070907
Cat. No.:
0225LY-0844
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
T0070907 acts as a highly specific and potent PPARγ inhibitor (IC50: 1 nM), demonstrating a selectivity profile over 800 times greater for the gamma subtype than for the alpha or delta subtypes.
Synonym:
313516-66-4; 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide; 2-chloro-5-nitro-N-pyridin-4-ylbenzamide; T 0070907; T-0070907; Benzamide, 2-chloro-5-nitro-N-4-pyridinyl-; MFCD00121849; 2-Chloro-5-nitro-N-(4-pyridyl)benzamide
CAS No.:
313516-66-4
Compound CID:
2777391
Formula:
C12H8ClN3O3
Formula Weight:
277.66
Specification
Targets&IC50:
PPARγ: 1 nM
Relative Density:
1.498 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
T0070907 can be used in cell signaling research as a potent and selective antagonist of the PPAR gamma receptor.
Library Information
Target:
PPAR
Receptor:
PPARα; PPARγ; PPARδ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
h3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
72.14 mg/mL; 259.81 mM
ALogP:
2.022
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
3
