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L755507
Cat. No.:
0225LY-1160
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
L755507 acts as a highly selective and efficient agonist of the β3-adrenoceptor, characterized by an IC50 value of 35 nM.
Synonym:
159182-43-1; L-755507; L-755,507; 1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea; L 755507; 3-hexyl-1-(4-{[4-(2-{[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)phenyl]sulfamoyl}phenyl)urea; 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]benzenesulfonamide
CAS No.:
159182-43-1
Compound CID:
9829836
Formula:
C30H40N4O6S
Formula Weight:
584.73
Specification
Targets&IC50:
β3-adrenoceptor: 35 nM
Relative Density:
1.274 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
L755507 can be used in receptor research to investigate the selective agonism of the beta-3 adrenergic receptor.
Library Information
Target:
Adrenergic receptor; CRISPR/Cas9
Receptor:
CRISPR/Cas9; β3-Adrenergic receptor
Pathways:
DNA damage/DNA repair; GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-15
Plate Location:
h7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
40 mg/mL; 68.41 mM
Ethanol Max Solubility:
58.5 mg/mL; 100.05 mM
ALogP:
4.413
HBA_Count:
4
HBD_Count:
6
Rotatable Bond:
17
