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CP-466722
Cat. No.:
OB0225WX-2340
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
CP-466722 is a reversible and effective ATM inhibitor that displays no inhibitory action against ATR, PI3K, or other members of the PIKK family in cellular environments.
Synonym:
CP 466722; CP466722; 1080622-86-1; 1-(6,7-dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-pyridin-2-yl-1,2,4-triazol-3-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-1,2,4-triazol-3-amine; MFCD17392566; 1-(6,7-Dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine; 2-(6,7-dimethoxy-4-quinazolinyl)-5-(2-pyridinyl)-1,2,4-triazol-3-amine; 2-(6,7-Dimethoxy-quinazolin-4-yl)-5-pyridin-2-yl-2H-[1,2,4]triazol-3-ylamine
CAS No.:
1080622-86-1
Compound CID:
44551660
Formula:
C17H15N7O2
Formula Weight:
349.35
Specification
Targets&IC50:
ATM: 410 nM
Relative Density:
1.48 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
CP-466722 is employed in laboratory experiments as a potent ATM inhibitor to examine the regulation of cell cycle checkpoints and the recruitment of repair proteins to double-strand breaks.
Library Information
Target:
ATM/ATR
Receptor:
ATM
Pathways:
DNA damage/DNA repair; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-31
Plate Location:
a2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
<1 mg/mL; insoluble or slightly soluble)





