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Vitamin B12 test kit

CP-466722

Cat. No.: OB0225WX-2340
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
CP-466722
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Product Overview

Description: CP-466722 is a reversible and effective ATM inhibitor that displays no inhibitory action against ATR, PI3K, or other members of the PIKK family in cellular environments.
Synonym: CP 466722; CP466722; 1080622-86-1; 1-(6,7-dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-pyridin-2-yl-1,2,4-triazol-3-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine; 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-1,2,4-triazol-3-amine; MFCD17392566; 1-(6,7-Dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine; 2-(6,7-dimethoxy-4-quinazolinyl)-5-(2-pyridinyl)-1,2,4-triazol-3-amine; 2-(6,7-Dimethoxy-quinazolin-4-yl)-5-pyridin-2-yl-2H-[1,2,4]triazol-3-ylamine
CAS No.: 1080622-86-1
Compound CID: 44551660
Formula: C17H15N7O2
Formula Weight: 349.35

Specification

Targets&IC50: ATM: 410 nM
Relative Density: 1.48 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: CP-466722 is employed in laboratory experiments as a potent ATM inhibitor to examine the regulation of cell cycle checkpoints and the recruitment of repair proteins to double-strand breaks.

Library Information

Target: ATM/ATR
Receptor: ATM
Pathways: DNA damage/DNA repair; PI3K/Akt/mTOR signaling
Plate Number: AOCL-31
Plate Location: a2
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: <1 mg/mL; insoluble or slightly soluble)
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