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Nateglinide
Cat. No.:
0225LY-0828
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Nateglinide is an amino acid derivative used as an oral hypoglycemic agent for type 2 diabetes; it stimulates pancreatic insulin secretion but has been associated with rare cases of acute liver injury.
Synonym:
A4166; Senaglinide; 105816-04-4; Starsis; Senaglinide; Fastic; AY-4166; Trazec; A-4166; SDZ-DJN-608; D-Nateglinide; DJN 608; DJN-608; MFCD00875706; (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid; N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine; N-[[trans-4-(1-methylethyl)cyclohexyl]carbonyl]-d-phenylalanine; N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine(Nateglinide Impurity); D-phenylalanine, N-((trans-4-(1-methylethyl)cyclohexyl)carbonyl)-; D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, cis-; D-Phenylalanine, N-[[trans-4-(1-methylethyl)cyclohexyl]carbonyl]-
CAS No.:
105816-04-4
Compound CID:
5311309
Formula:
C19H27NO3
Formula Weight:
317.42
Specification
Relative Density:
1.104 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Nateglinide can be used in endocrinology to study the rapid stimulation of insulin secretion through ATP-sensitive potassium channel closure.
Library Information
Target:
Potassium channel; Proteasome; PPAR
Receptor:
Dipeptidyl peptidase; Potassium channel; PPARγ
Pathways:
DNA damage/DNA repair; Ubiquitination; Proteases/Proteasome; Membrane transporter/Ion channel; Metabolism
Plate Number:
AOCL-11
Plate Location:
f7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 189.02 mM
ALogP:
3.981
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
6





