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Fenofibric acid
Cat. No.:
0225LY-0849
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Fenofibric acid is the active metabolic form of fenofibrate, representing a synthetic phenoxy-isobutyric acid derivative endowed with antihyperlipidemic properties.
Synonym:
Trilipix; FNF acid; 42017-89-0; Fenofibric acid; Procetofenic acid; 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid; Alpha 1081; LF 178 acid; LF 153; 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-; Fenofibricacid
CAS No.:
42017-89-0
Compound CID:
64929
Formula:
C17H15ClO4
Formula Weight:
318.75
Specification
Targets&IC50:
PPARα: 22.4 µM(EC50); PPARδ: 1.06 µM(EC50); PPARγ: 1.47 µM(EC50); COX-2: 48 nM
Relative Density:
1.286 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Fenofibric acid can be used in lipid research to examine the activation of PPAR alpha and its effect on triglyceride reduction.
Library Information
Target:
PPAR; COX; MMP
Receptor:
COX-2; MMP; PPARα
Pathways:
DNA damage/DNA repair; Proteases/Proteasome; Metabolism; Immunology/Inflammation; Neuronal signaling
Plate Number:
AOCL-11
Plate Location:
h8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 188.24 mM
ALogP:
4.159
HBA_Count:
3
HBD_Count:
0
Rotatable Bond:
5
