Palosuran

Cat. No.: OB0225WX-2261

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Palosuran is a potent and specific small molecule antagonist targeting the human urotensin-II (UT) receptor.

Synonym: ACT-058362; 540769-28-6; 1-(2-(4-Benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea; ACT058362 (Palosuran); 1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(2-methylquinolin-4-yl)urea; Urea, N-[2-[4-hydroxy-4-(phenylMethyl)-1-piperidinyl]ethyl]-N'-(2-Methyl-4-quinolinyl)-; 1-(2-(4-Benzyl-4-hydroxypiperidin-1-yl)ethyl-3-(2-methylquinolin-4-yl)urea; 1-[2-[4-hydroxy-4-(phenylmethyl)piperidin-1-yl]ethyl]-3-(2-methylquinolin-4-yl)urea; Urea, N-(2-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)ethyl)-N'-(2-methyl-4-quinolinyl)-; palosuranum; 1-(2-(4-hydroxy-4-(phenylmethyl)piperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea; ACT 058362; ACT 058362; Palosuran; 1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea sulfate salt; 1-[2-(4-Benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea

CAS No.: 540769-28-6

Compound CID: 10173280

Formula: C₂₅H₃₀N₄O₂

Formula Weight: 418.53

Specification

Targets&IC50: UT receptor (human): 3.6±0.2 nM

Relative Density: 1.235 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Palosuran is utilized in cardiovascular and renal research as a potent and selective urotensin II receptor antagonist to investigate the role of the urotensin system in vascular tone and fibrotic disease progression.