Product Overview
Description:
AdipoUpX™ Human GNAT3 MSCV Particle (Overexpression) is a professionally engineered retroviral vector designed for robust and stable overexpression of the human GNAT3 gene. GNAT3 is involved in taste receptor signaling and has emerging links to nutrient sensing and metabolic regulation, making it relevant for obesity and energy intake research. The MSCV system enables efficient genomic integration across hematopoietic stem cells, stem cells, and a broad range of mammalian cell lines, supporting long-term functional studies. Each batch is subjected to comprehensive quality control, including titer determination, sterility testing, and mycoplasma screening to ensure reproducibility and experimental safety.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
GNAT3
Full Name:
G protein subunit alpha transducin 3
Gene Symbol:
GDCA; HG1E
Summary:
GNAT3 encodes the alpha subunit of a heterotrimeric G protein involved in taste signal transduction. It mediates responses to sweet, bitter, and umami stimuli in taste receptor cells and is also expressed in gastrointestinal tissues. Beyond sensory perception, GNAT3 has been implicated in metabolic regulation, with genetic variation linked to metabolic syndrome traits.
