AdipoUpX™ Human MTCH2 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MTCH2 MSCV Particle (Overexpression) provides efficient stable overexpression of the human MTCH2 gene. MTCH2 is a mitochondrial outer membrane protein implicated in energy expenditure, mitochondrial metabolism, and genetic susceptibility to obesity. The MSCV system allows long-term gene integration in stem cells, hematopoietic stem cells, and other mammalian models. Product integrity and safety are ensured through extensive quality control testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: MTCH2

Full Name: Mitochondrial carrier 2

Gene Symbol: MIMP; HSPC032; SLC25A50

Gene ID: 23788

RefSeq ID-1: NP_001304160.1

RefSeq ID-2: NM_001317231.1

Summary: MTCH2 is a member of the mitochondrial carrier protein family (SLC25) localized in the inner mitochondrial membrane. It is highly expressed in white adipose tissue and is considered a key regulator of adipocyte biology. Human genetic studies have identified MTCH2 as a significant obesity-associated locus, suggesting it plays a pivotal role in determining fat storage capacity and mitochondrial energy efficiency.

AdipoUpX™ Human MTCH2 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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