XMD8-92

Cat. No.: OB0225WX-2171

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: XMD8-92 functions as a highly specific and effective inhibitor of the BMK1/ERK5 pathway, with a binding dissociation constant (Kd) of 80 nM.

Synonym: 1234480-50-2; XMD 8-92; 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-B][1,4]benzodiazepin-6-one; MFCD18782742; 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; XMD 8-92 (free base); 2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one; 2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one; 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-; 2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

CAS No.: 1234480-50-2

Compound CID: 46843772

Formula: C₂₆H₃₀N₆O₃

Formula Weight: 474.55

Specification

Targets&IC50: BMK1: 80 nM(Kd)

Relative Density: 1.301 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: XMD8-92 is utilized in molecular biology and oncology research as a potent and selective inhibitor of BMK1 (ERK5) to investigate the regulation of cell proliferation and the suppression of tumor growth.