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Tesaglitazar
Cat. No.:
0225LY-0832
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, ORP, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Tesaglitazar is a selective dual agonist for PPAR-alpha/gamma with a stronger affinity for the gamma receptor; while used in metabolic research, it has been noted to induce fibrosarcoma and DNA synthesis in certain rat cells.
Synonym:
251565-85-2; Galida; AZ 242; AZ-242; (S)-2-Ethoxy-3-(4-(4-((methylsulfonyl)oxy)phenethoxy)phenyl)propanoic acid; (S)-2-Ethoxy-3-{4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl}propionic acid; (2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic acid; Benzenepropanoic acid, alpha-ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]-, (alphaS)-
CAS No.:
251565-85-2
Compound CID:
208901
Formula:
C20H24O7S
Formula Weight:
408.47
Specification
Targets&IC50:
PPARγ: 0.2 μM(EC50); PPARα(human): 3.6 μM(EC50); PPARα (rat): 13.4 μM(EC50)
Relative Density:
1.278 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Tesaglitazar can be used in metabolic syndrome research to evaluate the therapeutic potential of dual PPAR alpha/gamma agonism.
Library Information
Target:
PPAR
Receptor:
PPARα; PPARβ; PPARγ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
f11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
260 mg/mL; 636.52 mM
