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Pioglitazone
Cat. No.:
0225LY-0907
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Pioglitazone is a thiazolidinedione insulin-sensitizing medication used to manage type 2 diabetes, though it has been associated with infrequent cases of acute liver damage.
Synonym:
U 72107; 111025-46-8; Actos; Glustin; Zactos; Pioglitazona; Pioglitazonum; 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione; 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione
CAS No.:
111025-46-8
Compound CID:
4829
Formula:
C19H20N2O3S
Formula Weight:
356.44
Specification
Targets&IC50:
PPARγ (mouse): 0.99 μM (EC50); PPARγ (human): 0.93 μM (EC50)
Relative Density:
1.26 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pioglitazone can be used in diabetes research or play a vital role in investigating the enhancement of insulin sensitivity through PPAR-gamma activation.
Library Information
Target:
PPAR
Receptor:
PPAR
Pathways:
DNA damage/DNA repair; Metabolism; Apoptosis
Plate Number:
AOCL-12
Plate Location:
f7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
28.8 mg/mL; 80.8 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
3.907
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
7
