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Cevoglitazar
Cat. No.:
0225LY-0872
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, ORP, and LC-MS.
Size:
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Product Overview
Description:
Cevoglitazar is a dual agonist of PPARɑ and PPARγ that has demonstrated the ability to significantly lower body weight and food consumption in cynomolgus monkeys and obese mice.
Synonym:
LBM-642; LBM 642; LBM642; 839673-52-8; (2R)-1-[4-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methoxy]phenyl]sulfonyl-2,3-dihydroindole-2-carboxylic acid; (R)-1-((4-((5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)methoxy)phenyl)sulfonyl)indoline-2-carboxylic acid; 1-[4-({5-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl}methoxy)benzene-1-sulfonyl]-2,3-dihydro-1H-indole-2-carboxylic acid
CAS No.:
839673-52-8
Compound CID:
10175076
Formula:
C27H21F3N2O6S
Formula Weight:
558.53
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Cevoglitazar can be used in metabolic pharmacology to study the dual agonism of PPAR alpha and gamma.
Library Information
Target:
PPAR
Receptor:
PPARα; PPARγ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
b11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 89.52 mM
