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LTURM34
Cat. No.:
0225LY-0675
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
LTURM34 is a DNA-PK inhibitor (IC50: 34 nM) with 170-fold selectivity over PI3K; it exhibits strong antiproliferative effects across diverse tumor cell populations.
Synonym:
1879887-96-3; 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one; 8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-benzo[e][1,3]oxazin-4-one; 8-dibenzothiophen-4-yl-2-morpholin-4-yl-1,3-benzoxazin-4-one
CAS No.:
1879887-96-3
Compound CID:
122705987
Formula:
C24H18N2O3S
Formula Weight:
414.48
Specification
Targets&IC50:
PI3Kβ: 5.8 μM; DNA-PK: 34 nM; PI4Kδ: 8.5 μM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
LTURM34 can be used in oncology studies to evaluate the specific inhibition of PIK3C3 and its impact on autophagy.
Library Information
Target:
PI3K; DNA-PK; PI4K
Receptor:
DNA-PK; PI3Kβ; PI3Kδ
Pathways:
PI3K/Akt/mTOR signaling; DNA damage/DNA repair
Plate Number:
AOCL-9
Plate Location:
g2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 144.76 mM
