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AMG131
Cat. No.:
0225LY-0850
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
AMG131 is a novel, selective PPARγ modulator from a non-thiazolidinedione (non-TZD) chemical class designed for the management of non-insulin-dependent (type 2) diabetes mellitus.
Synonym:
INT-131; AMG-131; CHS 131; 315224-26-1; Benzenesulfonamide, 2,4-dichloro-N-(3,5-dichloro-4-(3-quinolinyloxy)phenyl)-; Ibrigampar; INT131; AMG 131; 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide; 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide; 2,4-dichloro-N-(3,5-dichloro-4-quinolin-3-yloxyphenyl)benzenesulfonamide
CAS No.:
315224-26-1
Compound CID:
10229498
Formula:
C21H12Cl4N2O3S
Formula Weight:
514.21
Specification
Relative Density:
1.585 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
AMG131 can be used in metabolic research to explore the selective modulation of PPAR gamma for the treatment of insulin resistance.
Library Information
Target:
PPAR
Receptor:
PPARγ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
h9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
27.5 mg/mL; 53.48 mM
