Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
Caulophyllogenin
Cat. No.:
0225LY-0893
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Caulophyllogenin is a partial agonist of PPARγ (EC50 = 12.6 μM) sourced from the stem bark of Kalopanax pictus; it suppresses the release of pro-inflammatory cytokines and is applicable to research involving obesity, metabolic syndrome, type-2 diabetes, and various inflammatory conditions.
Synonym:
Segetalic acid; 52936-64-8; (4aR,5R,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-5,10-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; EINECS 258-265-5; MFCD00017384; (3beta,4alpha,16alpha)-3,16,23-Trihydroxyolean-12-en-28-oic acid; SCHEMBL2597674
CAS No.:
52936-64-8
Compound CID:
104361
Formula:
C30H48O5
Formula Weight:
488.7
Specification
Targets&IC50:
PPARγ: 12.6 μM (EC50)
Relative Density:
1.31 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Caulophyllogenin can be used in natural product research to explore the anti-inflammatory and anti-tumor properties of sapogenins.
Library Information
Target:
IL receptor; PPAR; TNF
Receptor:
TNF-α; PPARγ; IL-12; IL-6
Pathways:
DNA damage/DNA repair; Metabolism; Immunology/Inflammation; Apoptosis
Plate Number:
AOCL-12
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 204.62 mM
Water Max Solubility:
<1 mg/mL
