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(S)-Coriolic acid
Cat. No.:
0225LY-0837
Appearance:
Oil
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
(S)-Coriolic acid is a metabolite of 15-lipoxygenase and an endogenous PPAR-gamma ligand involved in cell differentiation; it can inhibit tumor cell adhesion to the vascular endothelium and down-regulate the IRGpIIb/IIIa receptor.
Synonym:
13(S)-HODE; 29623-28-7; (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid; 13-Hode; 13-Hydroxyoctadecadienoic acid; 13(S)-Hydroxyoctadeca-9Z,11E-dienoic acid; 13S-Hydroxy-9Z,11E-octadecadienoic acid; (13S)-Hydroxyoctadecadienoic acid; (+/-)-Coriolic acid; Coriolic acid, (+)-; Coriolic acid, (+/-)-; 13S-hydroxyoctadecadienoic acid; 13-hydroxy-9(z),11(e)-octadecadienoic acid; CHEBI:34154; 13(S)-Hydroxy-9(Z),11(E)-octadecadienoic acid; (9Z, 11E)-(13S)-13-Hydroxyoctadeca-9,11-dienoic acid; 9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13S)-; 13-Hydroxy-9,11-cis,trans-octadecadienoic acid; (S,9Z,11E)-13-Hydroxyoctadeca-9,11-dienoic acid; 9,11-Octadecadienoic acid, 13-hydroxy-, (E,Z)-
CAS No.:
29623-28-7
Compound CID:
6443013
Formula:
C18H32O3
Formula Weight:
296.44
Specification
Relative Density:
0.970 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
(S)-Coriolic acid can be used in lipid signaling research to investigate its role as a metabolic byproduct of linoleic acid.
Library Information
Target:
PPAR; Lipoxygenase
Receptor:
PPARγ; 15-LOX
Pathways:
DNA damage/DNA repair; Metabolism; Nuclear receptor signaling; Inflammation
Plate Number:
AOCL-11
Plate Location:
g6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 185.54 mM
Ethanol Max Solubility:
>50 mg/mL
Solubility:
Soluble in PBS and DMF
