Gemfibrozil

Cat. No.: 0225LY-0905

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Gemfibrozil is a fibric acid derivative that lowers lipid levels by stimulating PPARalpha-mediated fatty acid oxidation and lipoprotein lipase (LPL) synthesis; this process reduces apoC-III expression, leading to lower VLDL-C serum levels and an increase in HDL-C through the stimulation of apoA-I and apoA-II.

Synonym: CI-719; Jezil; Decrelip; Lopid; 25812-30-0; 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid; Lipur; Cholespid; Fibratol; Fibrocit; Gemfibril; Gemfibromax; Gemlipid; Hipolixan; CI-719; Gemfibrozilo; Gemfibrozilum; Renabrazin; Clearol; Elmogan; Fetinor; Gemnpid; Innogen; Ipolipid; Lanaterom; Lifibron; Lipigem; Lipizyl; Micolip; Normolip; Progemzal; Reducel; Regulip; Sinelip; Synbrozil; Taborcil; Tentroc; Brozil; Gozid; Hidil; Lipira; Gemd; Gevilon Uno; WL-Gemfibrozil; Gen-Fibro; Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-; Low-Lip; Gem-S; Lipozid; 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid; 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure

CAS No.: 25812-30-0

Compound CID: 3463

Formula: C₁₅H₂₂O₃

Formula Weight: 250.33

Specification

Targets&IC50: 2C19: 24 μM(Ki); 1A2: 82 μM(Ki); CYP2C9: 5.8 μM(Ki); 2C8: 69 μM(Ki)

Relative Density: 1.044 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Gemfibrozil can be used in cardiovascular studies to explore the modulation of triglyceride levels and its impact on atherosclerosis progression.