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Eplerenone (CGP 30083)
Cat. No.:
OB0225WX-2813
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Eplerenone functions as a specific mineralocorticoid receptor antagonist that blocks the physiological action of aldosterone.
Synonym:
CGP 30083; SC-66110; 107724-20-9; Eplerenone; Epoxymexrenone; Inspra; 107724-20-9; Selara; SC-66110; CGP-30083; Cgp 30083; HSDB 7522; SC-6611O; SC 6110; 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, methyl ester; 7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone; Methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-ene-9'-carboxylate; Methyl (1'R,2S,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-ene-9'-carboxylate
CAS No.:
107724-20-9
Compound CID:
443872
Formula:
C24H30O6
Formula Weight:
414.49
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Eplerenone is applied in cardiovascular research as a highly selective mineralocorticoid receptor antagonist to investigate the regulation of fluid balance and the prevention of aldosterone-mediated cardiac fibrosis.
Library Information
Target:
Mineralocorticoid receptor
Receptor:
Mineralocorticoid receptor
Pathways:
Endocrinology & Hormones
Plate Number:
L6700-13
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
2mM DMSO
DMSO Max Solubility:
10 mg/mL; 24.12 mM
ALogP:
0
HBA_Count:
0
HBD_Count:
0
Rotatable Bond:
0





