AdipoUpX™ Human ADIPOQ MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ADIPOQ MMLV Particle (Overexpression) is a high-titer MMLV particle designed for the efficient and stable overexpression of the human ADIPOQ gene. ADIPOQ codes for adiponectin, which is crucial for insulin sensitization and anti-inflammatory signaling. This MMLV system's stable integration into dividing cells makes it an ideal tool for investigating the protective roles of adipokines and establishing stable cell models. Overexpressing ADIPOQ enables researchers to study its systemic metabolic effects. The viral system offers high flexibility for customization.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: ADIPOQ

Full Name: Adiponectin, C1Q and collagen domain containing

Gene Symbol: ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1

Gene ID: 9370

RefSeq ID: NM_001177800.2, NP_001171271.1

Summary: ADIPOQ is unique as a gene expressed exclusively by adipose tissue, where it codes for the hormone adiponectin. This protein circulates widely and acts as an anti-inflammatory, insulin-sensitizing adipokine. Adiponectin is a protective factor whose plasma levels are typically reduced in obese and diabetic patients. Its primary therapeutic interest lies in its ability to enhance insulin signaling and stimulate fatty acid oxidation in muscle and liver, making it a critical biomarker and target for treatments aimed at improving metabolic health and reversing insulin resistance.

AdipoUpX™ Human ADIPOQ MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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