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URB602
Cat. No.:
0225LY-1318
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
URB602 is a noncompetitive and specific inhibitor of monoacylglycerol lipase (MGL), targeting the enzyme in the brain with an IC50 of 28 uM.
Synonym:
565460-15-3; Cyclohexyl biphenyl-3-ylcarbamate; Cyclohexyl [1,1'-biphenyl]-3-ylcarbamate; URB-602; URB 602; Biphenyl-3-ylcarbamic acid cyclohexyl ester; Carbamic acid, N-(1,1'-biphenyl)-3-yl-, cyclohexyl ester; Cyclohexyl N-(3-phenylphenyl)carbamate; Monoacylglycerol Lipase Inhibitor, URB602; Cyclohexyl [1,1-biphenyl]-3-ylcarbamate
CAS No.:
565460-15-3
Compound CID:
10979337
Formula:
C19H21NO2
Formula Weight:
295.38
Specification
Targets&IC50:
MGL: 28±4 μM
Relative Density:
1.149 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
URB602 can be used in neuroscience research to investigate the selective inhibition of monoacylglycerol lipase (MAGL) and its role in endocannabinoid signaling.
Library Information
Target:
Lipase; Bacterial protein
Receptor:
MGL; Bacterial protein
Pathways:
Microbiology/Virology; Metabolism
Plate Number:
AOCL-17
Plate Location:
h5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 186.2 mM
ALogP:
4.97
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
4
