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Brevianamide F
Cat. No.:
0225LY-1305
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Brevianamide F, also identified as cyclo-(L-Trp-L-Pro), is a natural 2,5-diketopiperazine that demonstrates significant inhibitory effects on breast cancer resistance protein.
Synonym:
Cyclo-L-tryptophyl-L-proline; Cyclo-(L-Trp-L-Pro); Cyclo(L-Pro-L-Trp); 38136-70-8; Cyclo-L-Trp-L-Pro; L-prolyl-L-tryptophan anhydride; Cyclo-(Trp-Pro); (3s,8as)-3-(1h-Indol-3-Ylmethyl)hexahydropyrrolo[1,2-A]pyrazine-1,4-Dione; Cyclo-L-Prolyl-L-tryptophanyl; Cyclo-L-tryptophanyl-L-proline; Tryptophan-proline diketopiperazine; Cyclo(L-Trp-L-Pro); L-tryptophyl-L-proline cyclic anhydride; Cyclo-L-proline-L-pryptophan; Cyclo-L-pryptophan-L-proline; (3S,8aS)-3-((1H-Indol-3-yl)methyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS No.:
38136-70-8
Compound CID:
181567
Formula:
C16H17N3O2
Formula Weight:
283.33
Specification
Targets&IC50:
PI3Kα: 4.8 μM (IC50)
Relative Density:
1.37 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Brevianamide F can be used in chemical biology to investigate the biosynthetic pathways of fungal secondary metabolites and their potential antimicrobial properties.
Library Information
Target:
BCRP; PI3K
Receptor:
BCRP; PI3K
Pathways:
Microbiology/Virology; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-17
Plate Location:
g2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 176.47 mM
