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Triciribine phosphate
Cat. No.:
OB0225WX-1635
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Triciribine phosphate is a water-soluble AKT inhibitor that exerts its biological effects by inducing cell cycle arrest and activating cysteinyl asparagin-dependent apoptotic pathways.
Synonym:
TCN-P; VD 002; VQD-002; 61966-08-3; Pentaazaacenaphthylene-5' phosphate ester; [(2R,3S,4R,5R)-5-(5-amino-7-methyl-2,6,7,9,11-pentazatricyclo[6.3.1.04,12]dodeca-1(12),3,5,8,10-pentaen-2-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; Triciribine-phosphate; Triciribine-5'-monophosphate; 3-Amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylene 5'-(dihydrogen phosphate); 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-(5-O-phosphono-.beta.-D-ribofuranosyl)-; 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-; [(2R,3S,4R,5R)-5-[amino(methyl)[?]yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate; 3-Amino-1,5-dihydro-5-methyl-1-.beta.-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylene 5'-(dihydrogen phosphate)
CAS No.:
61966-08-3
Compound CID:
43860
Formula:
C13H17N6O7P
Formula Weight:
400.28
Specification
Relative Density:
2.23 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Triciribine phosphate is utilized in experimental oncology to examine the suppression of Akt phosphorylation and its subsequent effects on the survival and proliferation of malignant cells.
Library Information
Target:
Akt
Receptor:
Akt
Pathways:
Cytoskeletal signaling; PI3K/Akt/mTOR signaling; Apoptosis
Plate Number:
AOCL-21
Plate Location:
h10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
2mM DMSO
DMSO Max Solubility:
1 mg/mL; 2.50 mM
Water Max Solubility:
5 mg/mL; 12.49 mM
