Products
Online Inquiry
SRT2183
Cat. No.:
OB0225WX-2742
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
SRT2183 is a small-molecule activator specifically targeting the SIRT1 sirtuin subtype, currently categorized as an investigational agent for sirtuin modulation.
Synonym:
1001908-89-9; SRT 2183; (R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide; SRT-2183; 2-Naphthalenecarboxamide, N-(2-(3-(((3R)-3-hydroxy-1-pyrrolidinyl)methyl)imidazo(2,1-b)thiazol-6-yl)phenyl)-; N-(2-(3-(((3R)-3-Hydroxy-1-pyrrolidinyl)methyl)imidazo(2,1-b)thiazol-6-yl)phenyl)-2-naphthalenecarboxamide; N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide; N-[2-(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]naphthalene-2-carboxamide; N-[2-(3-{[(3R)-3-Hydroxy-1-pyrrolidinyl]methyl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-naphthamide
CAS No.:
1001908-89-9
Compound CID:
24180126
Formula:
C27H24N4O2S
Formula Weight:
468.57
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SRT2183 is applied in metabolic and aging research as a selective SIRT1 activator to study the enhancement of mitochondrial biogenesis and the regulation of cellular stress resistance.
Library Information
Target:
Sirtuin
Receptor:
SIRT1
Pathways:
DNA damage/DNA repair
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
93 mg/mL; 198.48 mM
Ethanol Max Solubility:
3 mg/mL
ALogP:
3.6
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
5
