Products
Online Inquiry
lavendustin B
Cat. No.:
OB0225WX-1583
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Lavendustin B is a selective Tyrosine Kinase Inhibitor that functions by disrupting the interaction between HIV-1 integrase and its essential cellular cofactor, LEDGF/p75.
Synonym:
Lavendustin b; 125697-91-8; 5-(bis(2-hydroxybenzyl)amino)-2-hydroxybenzoic acid; 5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid; Benzoic acid, 5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-; 5-(Bis((2-hydroxyphenyl)methyl)amino)-2-hydroxybenzoic acid; 5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid; Benzoic acid, 5-(bis((2-hydroxyphenyl)methyl)amino)-2-hydroxy-; 5-(bis((2-hydroxyphenyl)methyl)amino)-2-hydroxybenzoate; 5-{bis[(2-hydroxyphenyl)methyl]amino}-2-hydroxybenzoate; 5-Amino-(N,N'-bis-2-hydroxybenzyl)salicylic acid; N,N-bis(2'-Hydroxybenzyl)-3-aminosalicylic acid
CAS No.:
125697-91-8
Compound CID:
3895
Formula:
C21H19NO5
Formula Weight:
365.38
Specification
Targets&IC50:
HIV-1 integrase-LEDGF/p75: 94.07 μM (IC50); GLUT1: 15 μM (Ki)
Relative Density:
1.423 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
lavendustin B is applied in signal transduction research as a tyrosine kinase inhibitor to study the regulation of cellular growth and the inhibition of protein phosphorylation.
Library Information
Target:
HIV protease; Tyrosinase; Transporter
Receptor:
GLUT; HIV Integrase; HIV-1 integrase; Tyrosinase; Tyrosine Kinase
Pathways:
Proteases/Proteasome; Microbiology/Virology; Metabolism
Plate Number:
AOCL-21
Plate Location:
c8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
65 mg/mL; 177.89 mM
