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Lanifibranor
Cat. No.:
0225LY-0851
Purity:
≥95%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Lanifibranor is a pan-PPAR agonist that activates the human alpha, sigma, and gamma subtypes with EC50 values of 1.5 μM, 0.87 μM, and 0.21 μM, respectively.
Synonym:
IVA337; 927961-18-0; IVA-337; Libfranor; 1H-Indole-2-butanoic acid, 1-(6-benzothiazolylsulfonyl)-5-chloro-; 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloroindol-2-yl]butanoic acid; 5-Chloro-1-((6-benzothiazolyl)sulfonyl)-1H-indole-2-butanoic acid; 4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid; 4-(1-(benzo[d]thiazol-6-ylsulfonyl)-5-chloro-1H-indol-2-yl)butanoic acid; 4-(1-(1,3-benzothiazole-6-sulfonyl)-5-chloro-1H-indol-2-yl)butanoic acid; 4-[1-(1,3-benzothiazole-6-sulfonyl)-5-chloro-1H-indol-2-yl]butanoic acid
CAS No.:
927961-18-0
Compound CID:
68677842
Formula:
C19H15ClN2O4S2
Formula Weight:
434.92
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Lanifibranor can be used in fibrosis research to investigate the therapeutic effects of pan-PPAR agonism in systemic sclerosis and NASH.
Library Information
Target:
PPAR
Receptor:
PPAR
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
h10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
ALogP:
4.676
HBA_Count:
4
HBD_Count:
0
Rotatable Bond:
6





