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Curcumenol
Cat. No.:
OB0225WX-2569
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Curcumenol is a sesquiterpene isolated from Curcuma zedoaria that blocks NF-kappaB activation by inhibiting I-kappa-B-alpha phosphorylation and suppressing the nuclear translocation of the p65 subunit.
Synonym:
19431-84-6; (+)-Curcumenol; BRN 3094585; 6H-3a,6-Epoxyazulen-6-ol, 1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-, (3S-(3-alpha,3a-alpha,6-alpha,8a-beta))-; 5-beta-Guiaia-7(11),9-dien-8-alpha-ol, 5,8-epoxy-; 6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-, (3S,3aS,6R,8aS)-; (1S,2S,5S,8R)-2,6-Dimethyl-9-propan-2-ylidene-11-oxatricyclo[6.2.1.01,5]undec-6-en-8-ol; 3,8-Dimethyl-5-(1-methylethylidene)-,(3S,3aS,6R,8aS)-; (1S,2S,5S,8R)-2,6-dimethyl-9-propan-2-ylidene-11-oxatricyclo(6.2.1.01,5)undec-6-en-8-ol; 9-isopropylidene-2,6-dimethyl-11-oxatricyclo(6.2.1.0^1,5^)undec-6-en-8-ol; 9-isopropylidene-2,6-dimethyl-11-oxatricyclo[6.2.1.0^1,5^]undec-6-en-8-ol; 5,8-Epoxy-9-dien-8-.alpha.-ol-5-.beta.-guiaia-7(11); 2,6-dimethyl-9-(propan-2-ylidene)-11-oxatricyclo(6.2.1.0^(1,5))undec-6-en-8-ol; 2,6-dimethyl-9-(propan-2-ylidene)-11-oxatricyclo[6.2.1.0^{1,5}]undec-6-en-8-ol; Curcumenol6H-3a,6-Epoxyazulen-6-ol, 1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-, (3S-(3-alpha,3a-alpha,6-alpha,8a-beta))-
CAS No.:
19431-84-6
Compound CID:
167812
Formula:
C15H22O2
Formula Weight:
234.33
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Curcumenol is utilized in phytochemical research as a sesquiterpene from Curcuma zedoaria to examine its anti-proliferative activities and its potential in inducing apoptosis in tumor cell lines.
Library Information
Target:
NF-κB; P450
Receptor:
NF-κB; P450
Pathways:
NF-κB
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
46 mg/mL; 196.3 mM
ALogP:
3.268
HBA_Count:
1
HBD_Count:
0
Rotatable Bond:
0





