Anlotinib (AL3818) dihydrochloride

Cat. No.: OB0225WX-2777

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Anlotinib is a highly selective and potent VEGFR2 inhibitor (IC50 < 1 nM) characterized by broad-spectrum tyrosine kinase inhibition.

Synonym: 1360460-82-7; Anlotinib dihydrochloride; Anlotinib HCl; Anlotinib hydrochloride; AL3818 dihydrochloride; Catequentinib Hydrochloride; 1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl]oxymethyl]cyclopropan-1-amine;dihydrochloride; Anlotinib 2HCl; 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine dihydrochloride; 1-[({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl}oxy)methyl]cyclopropan-1-amine dihydrochloride; 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]cyclopropanamine Hydrochloride (1:2); 1-((4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-quinolyl)oxymethyl)cyclopropanamine, dihydrochloride; 1-[[[4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropanamine dihydrochloride; Cyclopropanamine, 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-quinolinyl)oxy)methyl)-, hydrochloride (1:2); Cyclopropanamine, 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinoliny]oxy]methyl]-, hydrochloride (1:2)

CAS No.: 1360460-82-7

Compound CID: 57380530

Formula: C₂₃H₂₂FN₃O₃·2HCl

Formula Weight: 480.36

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Anlotinib (AL3818) dihydrochloride is employed in advanced oncology research as a multi-targeted tyrosine kinase inhibitor to study the simultaneous suppression of VEGFR, FGFR, PDGFR, and c-Kit in tumor angiogenesis and proliferation.