Products
Online Inquiry
AKT-IN-1
Cat. No.:
OB0225WX-1644
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
AKT-IN-1 is characterized as an allosteric inhibitor of the AKT kinase, exhibiting a half-maximal inhibitory concentration (IC50) of 1.04 μM.
Synonym:
AZD26; AZD-26; AZD 26; 1357158-81-6; 6-[4-(1-aminocyclobutyl)phenyl]-5-phenylpyridine-3-carboxamide; 6-(4-(1-Aminocyclobutyl)phenyl)-5-phenylnicotinamide; 6-[4-(1-Aminocyclobutyl)phenyl]-5-phenyl-3-pyridinecarboxamide
CAS No.:
1357158-81-6
Compound CID:
56953649
Formula:
C22H21N3
Formula Weight:
343.42
Specification
Targets&IC50:
Akt (allosteric): 1.04 μM
Relative Density:
1.210 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
AKT-IN-1 is applied in laboratory experiments as a potent Akt inhibitor to characterize the structural requirements for effective binding within the Akt kinase domain.
Library Information
Target:
Akt
Receptor:
Allosteric Akt
Pathways:
Cytoskeletal signaling; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-22
Plate Location:
a9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
11 mg/mL; 32.03 mM
