Vildagliptin (LAF-237)

Cat. No.: OB0225WX-2545

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

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Product Overview

Description: Vildagliptin (LAF-237) functions as a potent inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme, featuring a half-maximal inhibitory concentration (IC50) of 2.3 nM.

Synonym: NVP-LAF 237; 274901-16-5; Vildagliptin; Galvus; Xiliarx; Jalra; NVP-LAF237; Equa; LAF237; LAF-237; LAF 237; Vitagliptin; Vildagliptin (LAF-237); NVP-LAF 237; NVP-LAF-237; Vidagliptin (see Vildagliptin); (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile; (2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile; 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-; (2S)-(((3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; 2-Pyrrolidinecarbonitrile, 1-(((3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)amino)acetyl)-, (2S)-; (2S)-{((3-Hydroxyadamantan-1-yl)amino)acetyl}pyrrolidine-2-carbonitrile; (2S)-1-(((3-Hydroxytricyclo(3.3.1.13,7)dec-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; (2S)-1-{[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile

CAS No.: 274901-16-5

Compound CID: 6918537

Formula: C₁₇H₂₅N₃O₂

Formula Weight: 303.4

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Vildagliptin (LAF-237) is employed in metabolic studies as an orally active DPP-4 inhibitor to investigate the improvement of glycemic control and the preservation of pancreatic beta-cell function in diabetic models.