Pomalidomide (CC-4047)

Cat. No.: OB0225WX-2425

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Pomalidomide (CC-4047) is a ligand for the cereblon (CRBN) E3 ubiquitin ligase that inhibits LPS-induced TNF-alpha release (IC50: 13 nM) and is frequently utilized in the design of PROTAC molecules.

Synonym: CC-4047; 19171-19-8; Pomalidomide; Actimid; 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; Pomalyst; Imnovid; 4-Aminothalidomide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-; IMiD 3; CC 4047; IMID-3; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; CC4047; 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione; MFCD12756407; 3-Aminio-phthalimido-glutarimide; 4-Amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione; 4-Amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione; Phthalimide, 3-amino-N-(2,6-dioxo-3-piperidyl)-; 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; Pomalidomidum; Pomalidomid; Pomalidomida; 4-Amino-2-[(3RS)-2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione

CAS No.: 19171-19-8

Compound CID: 134780

Formula: C₁₃H₁₁N₃O₄

Formula Weight: 273.24

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Pomalidomide (CC-4047) is employed in immunology and oncology research as a potent immunomodulatory agent to study the degradation of transcription factors and the inhibition of TNF-alpha production in plasma cell dyscrasias.