Lenalidomide (CC-5013)

Cat. No.: OB0225WX-2387

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Lenalidomide is a ligand for the cereblon (CRBN) E3 ubiquitin ligase that induces the selective degradation of transcription factors IKZF1 and IKZF3 while inhibiting TNF-alpha secretion (IC50: 13 nM).

Synonym: CC-5013; 191732-72-6; Revlimid; Revimid; 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione; CC-5013; CDC 501; CDC-501; Lenalidomide (CC-5013); 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-; 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; IMiD3; CC 5013; 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione; Lenadoamide; MFCD07772307; (3S)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione; 3-(4-Amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione; IMiD3 cpd; lenalidomidum; Lenalidomida; 3-(4-Amino-1-oxo-2-isoindolinyl)piperidine-2,6-dione; 3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione; 2, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-; 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-dioxopiperidine; (3RS)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; 4-amino-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one

CAS No.: 191732-72-6

Compound CID: 216326

Formula: C₁₃H₁₃N₃O₃

Formula Weight: 259.26

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Lenalidomide is employed in hematology and immunology research as an immunomodulatory agent to investigate the degradation of specific ligase substrates and the inhibition of angiogenesis in multiple myeloma models.