Obacunone

Cat. No.: OB0225WX-2118

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Obacunone is a limonoid triterpene that exhibits cytotoxicity in androgen-dependent cells and exerts antivirulence effects by inhibiting aromatase enzymes and inflammatory signaling pathways.

Synonym: 751-03-1; Casimirolide; Obacunoic acid, eta-lactone; (1R,2R,4S,7S,8S,11R,12R,18R)-7-(furan-3-yl)-1,8,12,17,17-pentamethyl-3,6,16-trioxapentacyclo[9.9.0.02,4.02,8.012,18]icos-13-ene-5,15,20-trione; (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione; Oxireno(4,4a)-2-benzopyrano(6,5-g)(2)benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,11bR,13aS)-; 2-isopropenyl-5-methyl-furo[3,2-f]benzofuran-4,8-dione; 2-isopropenyl-5-methyl-furo(3,2-f)benzofuran-4,8-dione; (1R,2R,4S,7S,8S,11R,12R,18R)-7-(furan-3-yl)-1,8,12,17,17-pentamethyl-3,6,16-trioxapentacyclo(9.9.0.02,4.02,8.012,18)icos-13-ene-5,15,20-trione; MFCD00075888

CAS No.: 751-03-1

Compound CID: 119041

Formula: C₂₆H₃₀O₇

Formula Weight: 454.51

Specification

Targets&IC50: Aromatase: 28.4 μM

Relative Density: 1.32 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Obacunone is utilized in phytochemical and metabolic research as a natural limonoid to study its ability to activate the TGR5 receptor and improve glucose homeostasis.