Nocodazole (R17934)

Cat. No.: OB0225WX-2515

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Nocodazole (R17934) is a rapidly reversible inhibitor of microtubule polymerization that also targets Abl kinase isoforms, including mutant E255K and T315I, with sub-micromolar IC50 values.

Synonym: Oncodazole, NSC238159; 31430-18-9; Nocodazole; R 17934; Nocodazol; Nocodazolum; Methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate; methyl (5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate; NSC 238159; NSC-238159; R 17,934; Methyl 5-(2-thenoyl)-2-benzimidazolecarbamate; R-17934; Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; MFCD00005588; N-(5-(2-Thenoyl)-2-benzimidazolyl)carbamic acid methyl ester; NSC238159; Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate; 2-Benzimidazolecarbamic acid, 5-(2-thienylcarbonyl)-, methyl ester; 2-Benzimidazolecarbamic acid, 5-(2-thenoyl)-, methyl ester; Methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)carbamate; methyl (6-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate; Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester; Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)-, methyl ester; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester; Methyl 5-(2-thienoyl)-2-benzimidazolecarbamate; 2-Benzimidazolecarbamic acid, 5-(2-thienoyl)-, methyl ester; Methyl [5-(2-thienylcarbonyl)-1H- benzimidazol-2-yl]carbamate; methyl [6-(thiophen-2-ylcarbonyl)-1H-benzimidazol-2-yl]carbamate; N-(5-(2-Thienoyl)-2-benzimidazolyl)carbamic acid methyl ester; methyl N-[5-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate

CAS No.: 31430-18-9

Compound CID: 4122

Formula: C₁₄H₁₁N₃O₃S

Formula Weight: 301.32

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Nocodazole (R17934) is used in cell biology as a microtubule-destabilizing agent to investigate the dynamics of the cytoskeleton, mitosis regulation, and the induction of cell cycle arrest in the G2/M phase.