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AKT-I-1

Cat. No.: OB0225WX-1659
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
AKT-I-1
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Product Overview

Description: AKT-I-1 is defined as a selective and reversible chemical inhibitor specifically targeting the Akt1 isoform.
Synonym: 473382-39-7; Akt-l-1; N1-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N3,N3,2,2-tetramethylpropane-1,3-diamine; N3-(7-Cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine; Akt1-IN-2; N-(7-Cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine; Akt-I-1 compound; AktI 1; N'-(7-Cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2,2,N,N-tetramethyl-propane-1,3-diamine; N'-(7-Cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2,2,N,N-tetramethyl-propane-1.3-diamine
CAS No.: 473382-39-7
Compound CID: 10271028
Formula: C22H30N6
Formula Weight: 378.51

Specification

Relative Density: 1.20 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: AKT-I-1 is applied in molecular research as a selective allosteric inhibitor of Akt1 to study the isoform-specific contributions of Akt1 to cell growth and survival.

Library Information

Target: Akt
Receptor: Akt1
Pathways: Cytoskeletal signaling; PI3K/Akt/mTOR signaling
Plate Number: AOCL-22
Plate Location: c4
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 2mM DMSO
DMSO Max Solubility: 1.43 mg/mL; 3.77 mM
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