LipoKnoxa™ Human MCHR1 shRNA Lentiviral Particle (Silencing)

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX549-1	CCTCACCTTTGTCTACTTATA	CDS	Inquiry
V0126XX549-2	TCTCCCAAGCTGGTGGATAAT	3' UTR	Inquiry
V0126XX549-3	GATAACCGGTTGCACTATATC	3' UTR	Inquiry
V0126XX549-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human MCHR1 shRNA Lentiviral Particle (Silencing) targets MCHR1, involved in hunger stimulation. Engineered with both U6 and miR30-based shRNA systems, this tool enables the study of feeding behavior in stable cell lines. To ensure the highest level of biosafety, all products undergo total QC verification, including high functional titers and microbial checks.

Production Cell Line: HEK293T

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Comprehensive sequencing and PCR analyses were performed to verify the accurate genomic sequence of all viral preparations.

Sterility Test: Confirmed sterile via rigorous microbial analysis; free of bacterial and fungal contamination.

Mycoplasma Test: Rigorous quality control testing has confirmed the absence of mycoplasma contamination in this viral preparation.

Other QC: Customized supplementary testing and in vitro/in vivo assessments are available to verify post-silencing gene expression and biological functionality, ensuring the viral preparations meet the specific potency requirements of your gene interference project.

Storage: Store at -80°C for long-term preservation. Immediate transfer upon delivery is required to prevent loss of viral activity.

Stability: Shelf life: 6–12 months at -80°C (extended stability up to 2 years). Post-thaw: Stable at 4°C for 2–3 weeks without significant degradation of functional titers.

Shipping Condition: Products are delivered on dry ice to maintain the cold chain. Upon arrival, please ensure the presence of dry ice and transfer the vials immediately to -80°C storage.

Handling Notes: Avoid repeated freeze-thaw cycles. Aliquot into low-protein-binding tubes immediately after receipt to maintain optimal activity. For safety and contamination control, all viral handling must be performed inside a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: We ensure product integrity through rigorous QC, but we do not guarantee results in specific research contexts. Proper storage, handling, and total compliance with biosafety laws and safety protocols remain the sole responsibility of the user.

Target Profile

Gene Name: MCHR1

Full Name: Melanin concentrating hormone receptor 1

Gene Symbol: SLC1; GPR24; MCH1R; SLC-1; MCH-1R

Gene ID: 2847

RefSeq ID-1: NP_005288.3

RefSeq ID-2: NM_005297.3

Summary: MCHR1 encodes a G protein–coupled receptor for melanin-concentrating hormone, a neuropeptide that stimulates feeding behavior. Activation of this receptor modulates neuronal circuits governing appetite and energy balance, making MCHR1 a well-established target in obesity research.

LipoKnoxa™ Human MCHR1 shRNA Lentiviral Particle (Silencing)

Product Overview

Specification

Target Profile

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