IKK-16 (IKK Inhibitor VII)

Cat. No.: OB0225WX-2533

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: IKK-16 is a multi-IKK inhibitor targeting IKK-2, the IKK complex, and IKK-1 (IC50: 40 nM, 70 nM, and 200 nM) that also suppresses LRRK2 kinase activity.

Synonym: 873225-46-8; IKK Inhibitor VII; IKK 16; IKK-16; IKK-16 (IKK Inhibitor VII); IKK16; IKK-16 (free base); IKK Inhibitor; (4-((4-(Benzo[b]thiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone; 873225-46-8 (free base); [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone; [4-[(4-Benzo[b]thien-2-yl-2-pyriMidinyl)aMino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-Methanone; (4-{[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino}phenyl)[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone; 4-(1-benzothiophen-2-yl)-N-{4-[4-(pyrrolidin-1-yl)piperidine-1-carbonyl]phenyl}pyrimidin-2-amine; K00596a; MFCD23704180

CAS No.: 873225-46-8

Compound CID: 9549298

Formula: C₂₈H₂₉N₅OS

Formula Weight: 483.63

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: IKK-16 is employed in signal transduction research as a selective IKK complex inhibitor to investigate the disruption of the NF-kappaB signaling axis and its role in chronic inflammatory responses.