HA-100

Cat. No.: 0225LY-1084

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: HA-100 is categorized as an inhibitor of protein kinases.

Synonym: 84468-24-6; ha-100; 1-(5-Isoquinolinesulfonyl)piperazine; 5-(piperazin-1-ylsulfonyl)isoquinoline; Isoquinoline,5-(1-piperazinylsulfonyl)-; C-1; 5-(piperazine-1-sulfonyl)isoquinoline; 5-piperazin-1-ylsulfonylisoquinoline; HA 100 (pharmaceutical); Tocris-0543; 1-(5-Isoquinolinylsulfonyl)piperazine; C-I-QP; 1-(5-Isoquinolinesulfonyl)piperazine, dihydrochloride; 5-(1-Piperazinylsulfonyl)isoquinoline; Piperazine, 1-(5-isoquinolinylsulfonyl)-

CAS No.: 84468-24-6

Compound CID: 3545

Formula: C₁₃H₁₅N₃O₂S

Formula Weight: 277.34

Specification

Targets&IC50: PKG: 4 μM ; PKC: 12 μM; PKC: 6.5 μM (Ki); PKA: 8 μM ; MLCK: 240 μM ; MLCK: 61 μM (Ki)

Relative Density: 1.332 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: HA-100 can be used in cardiovascular studies to investigate the relaxation of smooth muscles through the inhibition of Rho-kinase and PKA.