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GSK1292263
Cat. No.:
OB0225WX-2263
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
GSK1292263 is a selective chemical agonist of the G-protein-coupled receptor GPR119.
Synonym:
1032823-75-8; GSK-1292263; 3-Isopropyl-5-(4-(((6-(4-(methylsulfonyl)phenyl)pyridin-3-yl)oxy)methyl)piperidin-1-yl)-1,2,4-oxadiazole; GSK-1292263A; GSK 1292263; GSK-263A; 5-[4-[[6-(4-methylsulfonylphenyl)pyridin-3-yl]oxymethyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole; 5-(((1-(3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl)-4-piperidinyl)methyl)oxy)-2-(4-(methylsulfonyl)phenyl)pyridine; 5-[[[1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl]methyl]oxy]-2-[4-(methylsulfonyl)phenyl]pyridine; Pyridine, 5-((1-(3-(1-methylethyl)-1,2,4-oxadiazol-5-yl)-4-piperidinyl)methoxy)-2-(4-(methylsulfonyl)phenyl)-; 2-(4-methanesulfonylphenyl)-5-((1-(3-(propan-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-4-yl)methoxy)pyridine; 2-(4-methanesulfonylphenyl)-5-({1-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-4-yl}methoxy)pyridine; 5-[({1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}methyl)oxy]-2-[4-(methylsulfonyl)phenyl]pyridine; MFCD18385004
CAS No.:
1032823-75-8
Compound CID:
24996872
Formula:
C23H28N4O4S
Formula Weight:
456.56
Specification
Relative Density:
1.23 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GSK1292263 is employed in metabolic research as a selective GPR119 agonist to investigate the stimulation of incretin hormone release and its potential role in enhancing glucose-dependent insulin secretion.
Library Information
Target:
GPR
Receptor:
GPR119
Pathways:
Endocrinology/Hormones; GPCR/G protein signaling
Plate Number:
AOCL-29
Plate Location:
h10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
32 mg/mL; 70.1 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
3.893
HBA_Count:
7
HBD_Count:
0
Rotatable Bond:
7





