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Gramine
Cat. No.:
0225LY-1181
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Gramine is a natural indole alkaloid that acts as an agonist for both the adiponectin receptors (AdipoR1/R2) and the β2-adrenergic receptor, possessing anti-viral, anti-tumor, and anti-inflammatory qualities.
Synonym:
NSC 16892; Donaxine; 87-52-5; 3-(Dimethylaminomethyl)indole; Donaxin; Gramin; 1-(1H-indol-3-yl)-N,N-dimethylmethanamine; 1H-Indole-3-methanamine, N,N-dimethyl-; Beta-Dimethylaminomethylindole; Indol-3-ylmethyldimethylamine; (1H-Indol-3-ylmethyl)-dimethyl-amine; 3-[(Dimethylamino)methyl]indole; 3-(N,N-Dimethylaminomethyl)indole; N,N-Dimethyl-1H-indole-3-methanamine; (Indol-3-ylmethyl)dimethylamine; (1H-indol-3-ylmethyl)dimethylamine
CAS No.:
87-52-5
Compound CID:
6890
Formula:
C11H14N2
Formula Weight:
174.24
Specification
Targets&IC50:
AdipoR2: 3.2 μM; AdipoR1: 4.2 μM
Relative Density:
0.7692 g/cm3 at 20°C.
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Gramine can be used in chemical biology or play an important role in studies concerning the synthesis of indole derivatives and plant defense mechanisms.
Library Information
Target:
Adiponectin receptor; Reverse transcriptase
Receptor:
Adiponectin receptor; Reverse transcriptase
Pathways:
Microbiology/Virology; GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-16
Plate Location:
b8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
120 mg/mL; 688.71 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
33 mg/mL; 189.39 mM
